A specific marker of severe bacterial infection and sepsis

Fully adapted for emergency conditions, VIDAS®B.R.A.H.M.S. PCTaids physicians in making rational clinical decisions and allows optimized patient management. Results are available in only 20 minutes.

Procalcitonin has been demonstrated to:

  • Help assess the severity and prognosis of an infection
  • Support early diagnosis of sepsis
  • Description
  • Technical Details


Procalcitonin (PCT) helps differentiate bacterial from viral infections, the early detection of an elevated PCT level in patients with suspected bacterial infections enabling earlier antibiotic treatment. PCT also supports informed decisions on when to continue or stop antibiotics, improving patient care and decreasing antibiotic misuse and resistance.

VIDAS® B.R.A.H.M.S PCT is an automated test for the determination of procalcitonin (PCT) in human serum or plasma.

Early Diagnosis and Monitoring

  • Early and highly specific marker for severe bacterial infection

Procalcitonin (PCT) is detected in the blood stream within 3 to 6 hours after an infectious challenge. It is upregulated in response to bacterial but not viral infections. The marker’s level rises with increasing severity of infection, and returns to normal as the infection resolves.

  • Useful tool to monitor treatment efficacy

PCT has a half-life of 24 hours. In adults, levels decrease daily by around 50% if the bacterial infection is controlled by the immune system supported by effective antibiotic therapy. Non-decreasing levels may point to treatment failure.

PCT impact on Antibiotic Therapy

Use of Procalcitonin in CRITICAL CARE: SEPSIS

In clinical studies including more than 1,000 ICU patients it has been demonstrated that the application of a decision algorithm based on the relative decrease of plasma PCT levels over time allows a significant reduction in the duration of antibiotic therapy and the length of ICU stay, without apparent harm to patients with severe sepsis and septic shock


Due to the high specificity of PCT for bacterial infection, PCT measurement at relatively low concentrations can identify patients with clinically relevant bacterial infection of the lower respiratory tract (LRTI) who require antibiotic therapy.

Assessment of Severity and Prognosis

It has been demonstrated that increased PCT values are the best indicator for the severity of infection and organ dysfunction8. As PCT levels correlate with severity of infection (as assessed by SOFA/Sequential Organ Failure Assessment score), an increase in PCT indicates progression of sepsis.

Solution adapted to Emergency Settings

Choose VIDAS® B.R.A.H.M.S PCT to take advantage of key benefits:

  • Rapid result: 20 minutes
  • Ease-of-use: 
    • Fully automated test on bench top VIDAS® instrument
  • Cost-effective solution:
    • Single-dose format
    • All reagents included in the kit
    • Monthly calibration
  • VIDAS® B.R.A.H.M.S PCT is part of a large VIDAS® Emergency Diagnostic solution, which also includes markers of cardiac necrosis, heart failure and thrombosis
Reference 30450
Tests / kit 60
Sample type Plasma (Lithium heparinate) or serum
Sample volume 200 uL
Time to result 20 minutes
Measuring Range 0.05 - 200ng/mL
Calibration stability 28 days