BCR-ABL P210 ELITe MGB Kit
The product of the Philadelphia translocation, the BCR/ABL oncogene P210 isoform, is typically found in chronic myelogenous leukemia, and in acute lymphoid and myeloid leukemia, causing the cells to divide uncontrollably and inducing severe outcomes among patients. Detection and quantification of P210 BCR-ABL fusion gene, by molecular methods, is crucial for patient management, to initiate the appropriate treatment, measure the response to therapy and predict relapse
Brands:Elitech
- Description
Description
Benefits
| Conserved targets | · Fusion gene and BCR-ABL, isoform P210 · Human gene ABL |
| One-step format | · Reverse transcription and real-time PCR assay within the same run |
| Best-in class PCR technology | · ELITe MGB probes designed with Minor Groove Binder, Superbases® and Eclipse® Dark Quencher |
| Large range of samples | · Peripheral blood samples, medullary blood samples collected in citrate or EDTA, lymphomonocyte or leukocyte suspensions |
| Instruments | · Extraction: TRI reagent product (Thermo Fisher Scientific) and Maxwell 16 (Promega) · Thermal cyclers: ABI 7300 Real-Time PCR system and ABI 7500 series |
| High performance | · 100% clinical sensitivity and 100% clinical specificity |
| Complete Onco-hematology menu | · Complete Onco-hematology menu with BCR-ABL P190 ELITe MGB® Kit & Philadelphia P210 RNA* |
