BCR-ABL P190 ELITe MGB Kit
The product of the Philadelphia translocation, the BCR/ABL oncogene P190 isoform, is commonly found in acute lymphoid leukemia, a rare disease that can be fatal within a matter of months if untreated. Detection and quantification of P190 BCR-ABL fusion gene, by molecular methods, is crucial for patient management, to initiate the appropriate treatment and measure response to therapy.
Brands:Elitech
- Description
Description
Benefits
| Conserved targets | · Fusion gene and BCR-ABL, isoform P190 · human gene ABL |
| One-step format | · Reverse transcription and real-time PCR assay within the same run |
| Best-in class PCR technology | · ELITe MGB probes designed with Minor Groove Binder, Superbases® and Eclipse® Dark Quencher |
| Large range of samples | · Peripheral blood samples, medullary blood samples collected in citrate or EDTA, lymphomonocyte or leukocyte suspensions |
| Instruments | · Extraction: TRI reagent product (Thermo Fisher Scientific) · Thermal cyclers: ABI 7300 Real-Time PCR system and ABI 7500 series |
| High performance | · 96% clinical sensitivity and 100% clinical specificity |
| Complete Onco-hematology menu | · Complete Onco-hematology menu with BCR-ABL P210 ELITe MGB® Kit and Philadelphia P210 RNA reference |
