Euroimmun

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    BIOCHIP Mosaics

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    BIOCHIP Mosaics

    BIOCHIP Mosaics for infectious serology

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    Euroimmun

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    Euroimmun

    Rheumatology is a sub-specialty devoted to the diagnosis and therapy of conditions and diseases affecting the joints, muscles, and bones. The term rheumatology originates from the Greek word rheuma, meaning ‘that which flows as a river or stream’, and the suffix –ology, meaning ‘the study of’.

    Rheumatology is a rapidly evolving medical specialty, with advancements owing largely to new scientific discoveries about the immunology of these disorders. Because the characteristics of some rheumatological disorders are often best explained by immunology, the pathogenesis of many major rheumatological disorders are now described in terms of the autoimmune system, viz., as an autoimmune disease.

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    Euroimmun

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    Euroimmun

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    EUROIMMUN microplate ELISA

    EUROIMMUN microplate ELISA

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    EUROLabWorkstation ELISA

    EUROLabWorkstation ELISA

    Efficient ELISA automation for high throughput

    Complete walk-away processing of ELISA from primary sample to end result

    • High capacities of up to 15 microplates and up to 700 samples in one run
    • Minimized hands-on times and high result integrity by software-guided loading and bar/matrixcode scanning of samples, reagents and accessories
    • Convenient ready-to-use reagents provided in all EUROIMMUN ELISA kits
    • Flexible work flow adaptation to varying requirements owing to a dynamic work place
    • High throughput of up to 200 tests per hour by fast pipetting of samples and reagents  with 10 pipetting channels and efficient processing of microplates
    • Flexible loading of the 45 tracks with patient samples, reagents and labware
    • Individual configuration with heatable incubators (shakers)
    • More than 200 EUROIMMUN ELISA validated for serum, plasma, and cerebrospinal fluid
    • Flexible open system for use with EUROIMMUN ELISA or other suppliers’ ELISA
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    Indirect immunofluorescence

    Indirect immunofluorescence
    Indirect immunofluorescence

    Indirect immunofluorescence

    Principle of the test

    • For the determination of autoantibodies or antibodies against infectious agents, cells, tissue sections or purified, biochemically characterized substances are used as antigen substrates.
    • If the sample is positive, specific antibodies in the diluted serum sample attach to the antigens coupled to a solid phase.
    • In a second step, the attached antibodies are stained with fluorescein-labelled anti-human antibodies and visualized with the fluorescence microscope.
    • Positive samples can be titrated in steps. The most suitable titration interval is provided by the dilution factor 3.162 (square root of 10). In this way, every second step represents in its denominator an integral power of 10 (1:10, 1:32, 1:100, 1 : 320, 1 : 1000, 1 : 3200, 1 : 10000 etc.).